Publication

/Publication/
25 03, 2012

The anomeric mixture of some O-galactolipid derivatives is more toxic against cancer cells than either anomer alone

Shao-Xing Song, Ming-Li Wu, Xiao-Peng He*, Yu-Bo Zhou, Li Sheng, Jia Li*, Guo-Rong Chen*

Bioorg. Med. Chem. Lett. 2012, 22, 2030-2032. DOI 10.1016/j.bmcl.2012.01.069

24 02, 2012

CuAAC Click Chemistry Accelerates the Discovery of Novel Chemical Scaffolds as Promising Protein Tyrosine Phosphatases Inhibitors

X.-P. He, J. Xie, Y. Tang, J. Li*, G.-R. Chen*

Curr. Med. Chem. 2012, 19, 2399-2405. DOI 10.2174/092986712800269245

23 11, 2011

Synthesis of (Glycopyranosyl-triazolyl)-purines and Their Inhibitory Activities against Protein Tyrosine Phosphatase 1B (PTP1B)

Lei Luo, Xiao-Peng He, Qiang Shen, Jing-Ya Li, Xiao-Xin Shi, Juan Xie*, Jia Li*, Guo-Rong Chen*

Chem. Biodiversity 2011, 8, 2035-2044. DOI 10.1002/cbdv.201000242

22 10, 2011

Synthesis of Triazole-Linked Amino Acid-Aryl C-Glycoside Hybrids via Click Chemistry as Novel PTP1B Inhibitors.

Jia Wang, Xiaopeng He, Lixin Gao, Li Sheng, Xiaoxin Shi, Jia Li*, Guorong Chen*

Chin. J. Chem. 2011, 29, 1227-1232.. DOI 10.1002/chin.201146185

21 10, 2011

Discovery of a sensitive Cu(ii)-cyanide “off–on” sensor based on new C-glycosyl triazolyl bis-amino acid scaffold

Yan-Hui Tang, Yi Qu, Zhuo Song, Xiao-Peng He*, Juan Xie, Jianli Hua*, Guo-Rong Chen*

Org. Biomol. Chem. 2011, 10, 555-560. DOI 10.1039/c1ob06242e

20 09, 2011

Click to a focused library of benzyl 6-triazolo(hydroxy)benzoic glucosides: Novel construction of PTP1B inhibitors on a sugar scaffold

Cui Li, Xiao-Peng He, Yin-Jie Zhang, Zhen Li, Li-Xin Gao, Xiao-Xin Shi, Juan Xie, Jia Li*, Guo-Rong Chen*, Yun Tang*

Eur. J. Med. Chem. 2011, 46, 4212-4218. DOI 10.1016/j.ejmech.2011.06.025

19 09, 2011

Discovering the distinct inhibitory effects between C4-epimeric glycosyl amino acids: new insight into the development of protein tyrosine phosphatase inhibitors

Xiao-Peng He, Cui Li, Zhi-Zhou Wang, Li-Xin Gao, Xiao-Xin Shi, Yun Tang, Juan Xie*, Jia Li*, Guo-Rong Chen*, Kaixian Chen

Glyconj. J. 2011, 28, 493-497. DOI 10.1007/s10719-011-9347-0

18 08, 2011

Disclosing the distinct interfacial behaviors of structurally and configurationally diverse triazologlycolipids

Xiao-Peng He, Xiaolian Xu, Hai-Lin Zhang, Guo-Rong Chen*, Shouhong Xu*, Honglai Liu

Carbohydr. Res. 2011, 346, 1320-1326. DOI 10.1016/j.carres.2011.04.038

17 07, 2011

Facile fabrication of promising protein tyrosine phosphatase (PTP) inhibitor entities based on ‘clicked’ serine/threonine–monosaccharide hybrids

Xiao-Peng He, Qiong Deng, Li-Xin Gao, Cui Li, Wei Zhang, Yu-Bo Zhou, Yun Tang, Xiao-Xin Shi, Juan Xie*, Jia Li*, Guo-Rong Chen*, Kaixian Chen

Bioorg. Med. Chem. Lett. 2011, 19, 3892-3900. DOI 10.1016/j.bmc.2011.05.049

16 06, 2011

6-O-Amino-2-O-carboxymethyl Glucopyranoside as Novel Glycoaminoxy Acid Building Block for the Construction of Oligosaccharide Mimetics

Zhuo Song, Xiao-Peng He, Guo-Rong Chen*, Juan Xie*

Synthesis 2011, 17, 2761-2766. DOI 10.1055/s-0030-1260139